Our interactive finder walks you through this step by step. This page is the flattened, skimmable version: the same situations, the same treatment tradeoffs, and the same six verified Missouri providers, all in one table so you do not have to click through several pages to compare them.
Methodology. Every row below restates a fact already published on this site, either in the quick-match section of our homepage, our treatment-types explainer, or our verified providers directory. No new claims, no new numbers. Compiled and pulled July 14, 2026.
1. Match your situation to a starting point
| If this sounds like you | Often fits |
|---|---|
| "I think I am depressed but have never been treated." | Therapy, first medication trial |
| "I have tried antidepressants and still feel stuck." | Worth asking about: TMS, Spravato, medication review |
| "My depression is tangled up with past trauma or PTSD." | Trauma-focused therapy, specialist evaluation |
| "I need help soon and cannot wait weeks." | 988 now; ask providers about their soonest evaluation |
Source: homepage quick-match, expanded in the full finder.
2. Compare the treatment types themselves
| Treatment | Tends to fit | Honest tradeoff |
|---|---|---|
| Talk therapy | Almost everyone, alone for milder depression or alongside medication for more severe symptoms | Takes time and effort; finding the right therapist can take a few tries |
| Antidepressant medication | Moderate to severe depression, or milder depression when therapy alone has not been enough | Finding the right medication and dose can involve trial and error |
| TMS | Treatment-resistant depression, or wanting to avoid or reduce medication | Requires a course of repeated visits; results vary person to person |
| Spravato (esketamine) | Treatment-resistant depression, used with an oral antidepressant under supervision | Must be given in a certified setting with monitoring, not something you take at home |
Source: the main depression treatments, compared.
3. See which verified providers offer what
| Provider | Location | Type |
|---|---|---|
| BJC Behavioral Health | St. Louis, MO | Community mental health, Medicaid accepted |
| Compass Health Network | Multiple locations across Missouri | Statewide, sliding scale |
| Burrell Behavioral Health | Springfield, Columbia, and central/southwest MO | Regional nonprofit, outpatient care |
| Saint Louis Behavioral Medicine Institute (SSM Health) | St. Louis, MO | Specialty outpatient, mood & anxiety programs |
| Washington University Psychiatry (WashU Medicine) | St. Louis, MO | Academic medical center, complex cases |
Source: verified Missouri depression & mental-health providers.
None of this replaces a real conversation with a clinician who knows your history. What it does is save you the trouble of piecing the same information together from three separate pages. For the interactive version with your own answers, use the full finder.
In St. Charles County or St. Louis County? Brain Recovery Centers is a doctor-supervised clinic in St. Peters offering FDA-approved Spravato and TMS for treatment-resistant depression and PTSD, and accepts most insurance including MO HealthNet. Disclosure: Brain Recovery Centers is a recommended, sponsored partner of this site and is featured separately from the independent providers table above.